Quick Answer: Why Was Chloroquine Discontinued?

Is there another name for chloroquine?

Chloroquine, brand name Aralen, is an anti-malarial drug.

It is similar to hydroxychloroquine (Plaquenil), and is useful in treating several forms of malaria as well as amebiasis that has spread outside of the intestines..

What plant is chloroquine made from?

The plant’s Latin name is Artemisia annua, but it is also known as “Sweet Annie,” “Sweet Wormwood” and also “Qing Hao,” arising from its origins in traditional Chinese medicine.

What is the difference between chloroquine and doxycycline?

allows prospects for reintroduction of this once useful drug. Moreover, chloroquine is effective in suppressing P. vivax infections, while doxycycline is very potent against multidrug-resistant strains of P. falciparum.

Is chloroquine used to treat lupus?

The two types of antimalarials most often prescribed today for lupus are hydroxychloroquine (Plaquenil®) and chloroquine (Aralen®). Unlike the rapid response seen with steroids, it may take months before antimalarial drugs improve your lupus symptoms. Side effects from antimalarials are rare and usually mild.

How is chloroquine prescribed?

To treat malaria: Chloroquine is usually given as one high dose followed by smaller doses during the next 2 days in a row. To treat amebiasis: Chloroquine is given in a high starting dose for 2 days followed by a smaller dose for 2 to 3 weeks. You may be given other medications to help prevent further infection.

Is chloroquine a steroid?

Steroid-sparing treatments have been sought and one of these is chloroquine. Chloroquine is an anti-inflammatory agent, also used in the treatment of malarial infection and as a second-line therapy in the treatment of rheumatoid arthritis, sarcoidosis and systemic lupus erythematosus.

Is malaria resistant to chloroquine?

Drug-resistant P. Chloroquine-resistant P. falciparum first developed independently in three to four areas in Southeast Asia, Oceania, and South America in the late 1950s and early 1960s. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted.

Is malaria a virus?

A: Malaria is not caused by a virus or bacteria. Malaria is caused by a parasite known as Plasmodium, which is normally spread through infected mosquitoes. A mosquito takes a blood meal from an infected human, taking in Plasmodia which are in the blood.

Why is chloroquine no longer used for malaria?

Chemoprophylaxis and treatment of falciparum malaria are becoming more complex because P. falciparum is increasingly resistant to various antimalarial drugs. Chloroquine can no longer be used for prevention and treatment of falciparum malaria.

Is chloroquine a prescription drug?

Chloroquine (also known as chloroquine phosphate) is an antimalarial medicine. It is available in the United States by prescription only. It is sold under the brand name Aralen, and it is also sold as a generic medicine.

Is chloroquine phosphate over the counter?

Can you buy chloroquine and proguanil over the counter? Chloroquine and proguanil is available as an over the counter medicine from your pharmacy, so you don’t need to see a doctor for a prescription in order to be able to buy it.

Is chloroquine still in use?

Chloroquine is still the drug of choice for sensitive malaria parasites although ACTs are used increasingly. Chloroquine is therefore used widely for P. vivax, P.

What is the purpose of chloroquine?

Chloroquine phosphate is used to prevent and treat malaria. It is also used to treat amebiasis. Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. It works by killing the organisms that cause malaria and amebiasis.

Is chloroquine banned in Nigeria?

Due to widespread reports of chloroquine ineffectiveness against the malaria parasite in endemic countries outside the African continent, the Federal Government of Nigeria officially banned the use of chloroquine in 2004.

Does chloroquine cause itching?

Study has shown that, 133 (40.20%) of 331 patients experienced itching to chloroquine and all those prone to itching to chloroquine did so after oral administration of the drug. Itching was reported to be more common among the families (first degree relations) of itchers but less common among those of non-itchers[9].

What is the difference between chloroquine and quinine?

Infected blood inoculated into volunteers was used to establish refractoriness to several synthetic antimalarials and support the efficacy of the quinine and pyrimethamine combination Quinine acts in a manner similar to that of chloroquine but with some differences; chloroquine causes clumping of the malaria pigment, …

What is the side effect of chloroquine?

Nausea, vomiting, abdominal cramps, headache, and diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Does chloroquine cause insomnia?

Among the adverse effects of chloroquine described in the literature and which are not often reported in malaria patients without treatment, there were reported changes in visual acuity (54%), insomnia (46%), pruritus (22%), the feeling of “stings” into the skin (22%), and paresthesias (6%).